It is used more and more frequently in the bodybuilding sector because, in combination with various steroids and peptides, it achieves an outstanding and extraordinary effect in the field of fat burning. The talk is of the thyroid hormone T3. All you should know about this is here:
T3 (Liothyronine, Cytomel) is a thyroid hormone, which is quite often used for fat reduction, especially in the context of steroid cycles. T3 is produced in the body naturally as a result of the T4, thus the Thyroxin production by the thyroid gland. Oral administration of T3 may lead to higher levels of T3 serum than would occur naturally, allowing faster fat loss, and in some cases potentially higher growth hormone production and faster metabolism.
The first thing to consider when dosing T3 is that the drug itself has a poor stability which results in a loss of potency over time which is the case even in pharmaceutical preparations in tablet form. Liquid preparations are even more susceptible to loss of effect. The dosages given below refer to T3 with full potency, as is the case with pharmaceutical products whose shelf life date has not expired. In many cases, other T3 products will contain less or much less T3 than indicated on the label.
For this reason, it is recommended to search for pharmaceutical T3, preferably of American or European origin. Otherwise, the dosage may be uncertain and deceptive. A person could perceive e.g. a 150 mcg dosage as an appropriate dosage when using a low-potency product but 150 mcg of a fully effective product as an extreme overdose.
In the first approach, the goal is to achieve a sustained lead in fat loss, or to help maintain a virtually ideal personal body composition. In this approach, the T3 dosage is very low and is preferably 12.5 mcg / day but in some cases also up to 25 mcg per day. At the lower end of this range, thyroid tests will typically show no detectable suppression of thyroid function, even in long-term use. At the upper end, a moderate suppression is sometimes observed, but the results are better than when no T3 is used and the suppression is rapidly reversible after discontinuation of T3.
In the second approach, the goal is to achieve a fairly constant increase in the rate of fat loss, with a suppression of thyroid function being accepted. The dosage preferably used is about 50 mcg per day, but may also be up to 75 mcg per day in some cases. Such use should preferably not take place in the long term, but only for a limited period of time, such as 8 to 12 weeks, even if there is no need for an exact period of time.
Since T3 has only a short half-life, one intake distributed over the day should be preferred to a single dose per day if the daily total dose is not very low. A dosage of 12.5 mcg per day would e.g. preferably be taken at once in the morning, but at a dosage of 50 mcg per day, it would be better to divide the total daily dose to three or four doses distributed throughout the day, than to take the whole quantity at once.
After a prolonged use of T3 in a suppressing dosage, the natural thyroid hormone production is suppressed for some time after the end of the T3 intake. In general, the duration appears to be related to the length of use. In the case of short-term use, there is typically no marked phase of low thyroid function after use, but in a long-lasting T3 intake cycle the duration of low thyroid function may be up to 6 weeks in some cases.
High doses of T3, which typically start at around 75 mcg / day, but do not start before 100 mcg / day in some cases, may result in an accelerated heart rate and muscle weakness, act catabolic, or at least reduce anabolism. High doses of anabolic steroids naturally tend to mask the latter effect.
High T3 levels reduce IGF-1 levels, which can reduce the anabolic effectiveness of growth hormones, but they do not alter the effectiveness of growth hormones for fat loss.
This brings some to believe that T3 reduces the side effects of growth hormones. In reality, however, T3 causes that the same dose of growth hormones produces less IGF-1 in the body than usual. It would be more effective to simply reduce growth hormone dosage to a personally appropriate level.
The effect of reducing the efficacy of growth hormones is particularly pronounced at T3 dosages above 50 mcg per day and does not appear to be noticeable, if present at all, if dosages such as 25 mcg T3 per day are used.