Salbutamol is a short-acting B2-adrenergic receptor agonist used for the relief of bronchospasm in such conditions as asthma and chronic obstructive pulmonary disease. Bodybuilders have used the drug, off label, for fat loss and to increase performance.
Medically, Salbutamol is not a corticosteroid or catabolic steroid. In fact, it stimulates the beta receptors, which causes vasodilatation (increased blood flow, pumps). Furthermore, it reduces stored fat by stimulating the break down of fatty acids into the blood stream for use as fuel. The boost in blood flow does come at a cost, which is increased heart rate. Therefore, Salbutamol may be a poor choice for endurance athletes or runners who need to increase their max heart rate.
Salbutamol increases body temperature and basal metabolic rate, and it decreases your appetite. Stimulants tend to cause appetite suppression, so Salbutamol does this very well. Since stimulating beta 2 receptors will boost energy expenditure and free up body fat to be used as fuel, Salbutamol can be considered anti-catabolic as well. However, huge bodybuilders may not care about this result, as they are already taking anabolic steroids, which are actually 'anabolic'. Hence, taking something 'anti-catabolic' as Salbutamol for muscle gain seems useless to them.
Generally, Salbutamol is used by bodybuilders for fat loss. However, some studies show that Salbutamol can help increase strength when used with a resistance training regiment. As stated above, it is doubtful that an advanced athlete, who routinely takes anabolic steroids, will notice much of anything from Salbutamol in regards to strength gains. Typically, bodybuilders will use Salbutamol to increase fat loss as part of their supplement/anabolic steroid stack during cycles. It's an aid to a cycle rather than a stand-alone drug.
Detection time of Salbutamol is short, only 24 hours. This is due to the short elimination half life of the drug. The half life of Salbutamol is 3.8 to 6 hours, which is why the drug is taken in split dosages throughout the day.
Salbutamol cycles can be run in one of two manners: a 2 weeks on followed by 2 weeks off protocol, or a constant use of Salbutamol with no breaks for no longer than an 8 week period provided that Ketotifen Fumarate is utilized for the purpose of beta-2 receptor up regulation at least once every two weeks (or when fat loss begins to slow down). Normally when beta-2 receptor down regulation has become significant, body temperature (which normally rises above baseline measurements while using Salbutamol) will return to baseline, indicating that the metabolism has slowed down. Salbutamol cycles should not be run for total periods longer than 3 - 4 months if the user is engaging in periodic breaks (such as the 2 weeks on / 2 weeks off protocol), or for periods of no longer than 8 - 10 weeks of constant uninterrupted use.
Generally, for adults its 2 puffs every 4-6 hours, with tablets its 2-4mg orally 3-4 times per day. For male bodybuilders, 4mgs 3 times a day (12mgs total) in tablet form is a moderate dosage for fat loss. Women will take about 6mg a day split dose. It is important to drink plenty of water and I recommend the drug be taken with some light food. If symptoms become an issue, the dose should be lowered, and if symptoms are tolerable, the athlete can increase the dose slightly.
Salbutamol can commonly be stacked and used with anabolic steroids to enhance its fat loss and anabolic effects, and as such, is normally combined with anabolic steroids that would normally be utilized to facilitate fat loss and/or lean muscle gain rather than bulking compounds. These would be compounds such as Winstrol (Stanozolol), Trenbolone, Masteron (Drostanolone), Anavar (Oxandrolone), Primobolan (Methenolone), and Turinabol (Chlorodehydromethyltestosterone). Such compounds promote lean mass without the risk of bloating or fat gain from estrogenic side effects. Salbutamol cycles can and are often run with other fat loss compounds, such as T3 (Triiodothyronine) and Human Growth hormone, but should not be combined with other stimulant based fat loss compounds such as Clenbuterol or Ephedrine. This is because of the compounding effects of these stimulants on the body. Negative cardiovascular effects as well as excessive stress on the CNS (Central Nervous System) can result, and so the practice of combining stimulant based fat loss agents should be avoided at all costs.