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Like the well-known PEG MGF, MGF is a peptide that should not be missing in most peptide stacks. Due to its potency, it is able to significantly increase the effect of other peptides while increasing HGH secretion and IGF1 production. Everything else about this peptide can be found here:


MGF, short for Mechano Growth Factor, is a variant of the body's growth hormone IGF-1, also known as IGF-1 EC. It affects reactions in the muscle tissue that appear under load and damages circulated through the eventual growth processes. MGF plays an important role in the supply and reinforcing effects of growth hormones, especially of IGF-1. In addition, MGF can greatly affect very different effects such as the promotion of so-called satellite cells, the precursor of new muscle tissue, as well as the division of these cells, which ultimately leads to a greatly increased muscle growth and largely limits the muscle reduction.


When stimuli develop in the musculature or heavy loads are triggered, especially through strength training, the combination of testosterone, insulin and HGH releases the strongest growth hormone IGF-1 and feeds the hormones involved, resulting in a stronger effect. Above all, this early splicing stimulates the radical formation of satellite cells, which in turn increasingly generates new muscle tissue and generally increases existing muscle mass. In addition, the protein synthesis is accelerated. This is one of the simplest, but in the end most effective hormonal processes in the body. MGF thus serves to splice hormones so much that the final IGF-1 release that is crucial for the development of new muscle tissue and for the growth of muscle mass in general.

Interestingly, in contrast to, for example, GHRP and other peptides, where the effect comes of increased growth hormone release, the effect of PEG MGF actually comes from the IGF1-like structure of Mechano Growth Factor, IGF1ec, which acts almost like IGF1, with a stronger anabolic component.


As with many other peptides, the opinions of personalities are different. Because MGF (MECHANO - GROWTH - FACTOR) has an effect similar to IGF - 1, many users inject between 100 and 200 mcg divided into each of the trained muscle groups.

However, as has been found, the effect of MGF on localized muscle growth has not been established. The most effective method has been to inject 200 mcg subcutaneously 2 times a week, at best on non-training days, at regular intervals, for 4 weeks.

MGF is most commonly combined with IGF1 LR3 because it affects both insulin-like growth factor 1 and mechano growth factor, generating the maximum muscle gain in the combination.


Interestingly, in spite of the potent effect of this peptide, very few regularly occurring side effects are known in MGF. The known side effects include:

  • Fatigue
  • Headaches
  • Temporary water retention

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