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1,3 Dimethylamylamine is also known as DMAA. It is an incredibly potent organic compound and stimulant that is extracted from geraniums. While it is more commonly used as a pre-workout supplement by athletes and bodybuilders, 1,3 Dimethylamylamine also has a wide range of nootropic effects that can improve mental performance.


Although all of the mechanisms of action for this supplement are still not fully understood, there is general acceptance by experts and researchers that DMAA primarily acts to release the powerful neurotransmitter norepinephrine.

This is one of the adrenal neurotransmitters that controls our levels of attention, focus, energy, motivation and mental alertness.

The supplement is normally absorbed into the bloodstream through the intestinal tract and is then capable of crossing over the blood-brain barrier. This effectively allows entry into the central nervous system.

There is also some evidence to suggest that 1, 3 Dimethylamylamine stimulates the release of dopamine, another powerful mood enhancing neurotransmitter.

Dopamine is responsible for executive function related to focus and concentration as well as controlling movement and serving as part of our rewards system positive feedback loop.


DMAA is a central nervous system stimulant and there are a large number of potential benefits related to cognitive ability. Primarily, this means a considerable increase in energy and focus.

This can help many people from athletes and students, stay-at-home moms to workers in a professional setting. Additionally, DMAA has been known to heighten the senses and even lead to a sense of euphoria (probably due to the increased release of dopamine).

The supplement is especially useful for weight training athletes. Due to the increase in energy, it can be an excellent pre workout aid. The added focus and motivation can help lessen your tolerance to pain, improve your stamina and allow you to power through and complete intense training sessions.

An interesting benefit is vasoconstriction, meaning that it tends to restrict blood flow and is an effective method to stimulate muscle growth at a much lower level of intensity. Blood pressure will increase at a dose dependent rate, but without a corresponding increase in heart rate.

Due to the stimulant effects, this supplement may also be valuable for fat loss. This seems to have a thermogenic effect, raising the metabolism and enabling more efficient use and burning of fat. Studies have shown this supplement, when combined with caffeine and other typical commercial fat burner ingredients, to increase metabolic rate by 35% over a placebo.


The typically recommended DMAA dosage is between 25 and 75 mg. This can be taken up to several times a day, but generally only one daily administration is needed and recommended.

It is often used about 30 minutes before an intense study session or workout, or at any time when you think a shot of extra energy may come in handy.

The positive effects of this supplement last for a few hours, although people who do not experience an energy 'crash' may find this to last even longer.


There have been a number of reports of side effects associated with this supplement. The most common of these is a noticeable lack of energy or 'crash' a few hours or so after taking DMAA. Of course, some people do not experience this at all. Additional side effects can include a significant increase in blood pressure. In extremely rare situations, it may also lead to an increased heart rate.

Most of the dangerous side effects which have been reported to the FDA are due to users taking much higher than recommended doses. Many of these users end up taking up to 500 or even 1,000 mg per day. Please do not exceed 25-75 mg at a time, and limit usage to no more than once or twice per day.

You should also not be combining 1, 3 Dimethylamylamine with other central nervous system stimulants or nootropics that have an effect on the adrenergic systems. Since this is a stimulant, it also may be a good idea to consider not using the supplement every day.

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